MACiE Home PageMACiE, which stands for Mechanism, Annotation and Classification in Enzymes, is a collaborative project between the Thornton Group at the European Bioinformatics Institute and the Mitchell Group at the University of St Andrews.
MACiE contains 335 fully annotated enzyme reaction mechanisms, which comprise 321 EC numbers (182 EC sub-subclasses) and 372 distinct CATH codes.